RegTransBase captures the knowledge in published scientific literature using a controlled vocabulary. RegTransBase describes a large number of regulatory interactions reported in many organisms and contains various types of experimental data, in particular:

• the activation or repression of transcription by an identified direct regulator
• determining the transcriptional regulatory function of a protein (or RNA) directly binding to DNA or RNA
• mapping or prediction of binding sites for a regulatory protein
• characterization of regulatory mutations

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Our analysis section of RegtransBase is based on a set of manually curated alignments of transcription factor binding sites and allows you to search for new binding sites and verify conservation of bindings sites across multiple species through the use of web based analysis tools.

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